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Publications Since 2000

  1. Currier TA, Etchegaray MA, Haight JL, Galaburda AM, Rosen GD. The effects of embryonic knockdown of the candidate dyslexia susceptibility gene homologue Dyx1c1 on the distribution of GABAergic neurons in the cerebral cortex. Neuroscience, 2011;172,535-546. DOI10.1016/j.neuroscience.2010.11.002, PMCID: PMC3010415.
  2. Threlkeld SW, Hill CA, Cleary CE, Truong DT, Rosen GD, Fitch RH. Teratogen-induced heterotopia leads to deficits in complex auditory discrimination and spatial learning in rats. J Neurodevelop Disord, 2010;1, 237-250. DOI 10.1007/s11689-009-9026-7
  3. Takahashi E, Dai G, Wang, R, Ohki K, Rosen GD, Galaburda AM, Grant PE, Wedeen VJ. Development of cerebral fiber pathways in cats revealed by diffusion spectrum imaging. Neuroimage, 2010;49(2):1231–40. PMID: 19747553. PMCID: PMC2789885.
  4. Takahashi E, Dai G, Rosen GD, Wang R, Ohki K, Folkerth RD, Galaburda AM, Wedeen VJ, Grant PE. Developing neocortex organization and connectivity in cats revealed by direct correlation of diffusion tractography and histology. Cereb Cortex. 2010
  5. Szalkowski CE, Hinman J, Threlkeld SW, Yu L., LePack A., Rosen GD, Chrobak JJ, LoTurco JJ, Fitch RH. Persistent spatial working memory deficits in rats following in utero RNAi of Dyx1c1. Genes Brain Behav, 2010. doi:10.1111/j.1601-183X.2010.00662.x
  6. Peschansky VJ, Burbridge TJ, Volz AJ, Fiondella C, Wissner-Gross Z, Galaburda AM, LoTurco JJ, Rosen GD. The Effect of variation in expression of the candidate dyslexia susceptibility gene homolog Kiaa0319 on neuronal migration and dendritic morphology in the rat. Cereb Cortex, 2009; Advance Access published on August 13, 2009; doi: doi:10.1093/cercor/bhp154.
  7. Manent JB, Wang Y, Chang Y, Paramasivam M, LoTurco JJ (2009) Dcx reexpression reduces subcortical band heterotopia and seizure threshold in an animal model of neuronal migration disorder. Nat Med 15:84-90.
  8. Fitch, R.H., Breslawski, H., Rosen, G.D. & Chrobak, J. 2008b. Persistent spatial working memory deficits in rats with bilateral cortical microgyria. Behavioral and Brain Functions, 4, 45.
  9. Fitch RH, Threlkeld SW, McClure MM, Peiffer AM. Use of a modified prepulse inhibition paradigm to assess complex auditory discrimination in rodents. Brain Res Bull. 2008; 76:1-7.
  10. LoTurco JJ, Kriegstein AR Manipulating midbrain stem cell self-renewal. Cell Stem Cell. 2008; 2:405-406.
  11. Higgins NC, Escabi MA, Rosen GD, Galaburda AM, Read HL. Spectral processing deficits in belt auditory cortex following early postnatal lesions of somatosensory cortex Neuroscience 2008;153(2):535-49.
  12. Threlkeld SW, Penley SC, Rosen GD, Fitch RH. Detection of silent gaps in white noise following cortical deactivation in rats Neuroreport. 2008;19(8):893-8.
  13. Järvinen-Pasley A, Bellugi U, Reilly J, Mills DL, Galaburda A, Reiss AL, Korenberg JR. Defining the social phenotype in Williams syndrome: a model for linking gene, the brain, and behavior. Dev Psychopathol. 2008; 20:1-35
  14. Burbridge TJ, Wang Y, Volz AJ, Peschansky VJ, Lisann L, Galaburda AM, LoTurco JJ, Rosen GD. Postnatal analysis of the effect of embryonic knockdown and overexpression of candidate dyslexia susceptibility gene Dcdc2. Neuroscience. 2008;In Press.
  15. Ward TS, Rosen GD, von Bartheld CS. Optical disector counting in cryosections and vibratome sections underestimates particle numbers: Effects of tissue quality. Microsc Res Tech. 2008;71:60-68.
  16. Young-Pearse TL, Bai J, Chang R, Zheng JB, LoTurco JJ, Selkoe DJ. A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference. J Neurosci 2007; 27:14459-14469.
  17. Ackman, J., Raddy L. Ramos, Matthew R. Sarkisian, and Joseph J. LoTurco. Citron Kinase is Required for Postnatal Neurogenesis in the Hippocampus. Dev Neurosci. 2007;29(1-2):113-23.
  18. Escabí MA, Higgins NC, Galaburda AM, Rosen GD, Read HL. Early cortical damage in rat somatosensory cortex alters acoustic feature representation in primary auditory cortex. Neuroscience. 2007;150(4):970-83.
  19. Threlkeld SW, Rosen GD, Fitch RH (2007) Age at developmental cortical injury differentially alters corpus callosum volume in the rat. BMC Neurosci 8:94.
  20. Paramasivam, M., Y.J. Chang, and J.J. Loturco, ASPM and Citron Kinase Co-Localize to the Midbody Ring During Cytokinesis. Cell Cycle, 2007. 6(13).
  21. Rosen GD, Bai J, Wang Y, Fiondella CG, Threlkeld SW, Loturco JJ, Galaburda AM. Disruption of Neuronal Migration by RNAi of Dyx1c1 Results in Neocortical and Hippocampal Malformations. Cereb Cortex. 17(11):2562-2572.
  22. Threlkeld SW, McClure MM, Bai J, Wang Y, Loturco JJ, Rosen GD, Fitch RH. Developmental disruptions and behavioral impairments in rats following in utero RNAi of Dyx1c1. Brain Res Bull. 2007;71(5):508-14.
  23. Eckert MA, Galaburda AM, Karchemskiy A, Liang A, Thompson P, Dutton RA, Lee AD, Bellugi U, Korenberg JR, Mills D, Rose FE, Reiss AL. Anomalous sylvian fissure morphology in Williams syndrome. Neuroimage. 2006;33(1):39-45.
  24. Gaser C, Luders E, Thompson PM, Lee AD, Dutton RA, Geaga JA, Hayashi KM, Bellugi U, Galaburda AM, Korenberg JR, Mills DL, Toga AW, Reiss AL. Increased local gyrification mapped in Williams syndrome. Neuroimage. 2006;33(1):46-54.
  25. Ackman JB, Siddiqi F, Walikonis RS, LoTurco JJ. Fusion of microglia with pyramidal neurons after retroviral infection. J Neurosci. 2006 Nov 1;26(44):11413-22
  26. Ackman, J.B. and J.J. Loturco, The potential of endogenous neuronal replacement in developing cerebral cortex following hypoxic injury. Exp Neurol, 2006.
  27. Eckert MA, Galaburda AM, Mills DL, Bellugi U, Korenberg JR, Reiss AL. The neurobiology of Williams syndrome: cascading influences of visual system impairment? Cell Mol Life Sci. 2006;63(16):1867-75.
  28. Eckert MA, Tenforde A, Galaburda AM, Bellugi U, Korenberg JR, Mills D, Reiss AL. To modulate or not to modulate: differing results in uniquely shaped Williams syndrome brains. Neuroimage. 2006;32(3):1001-7.
  29. Galaburda AM, Loturco J, Ramus F, Fitch RH, Rosen GD. From genes to behavior in developmental dyslexia. Nat Neurosci. 2006;9(10):1213-7.
  30. LoTurco, J.J. and Bai, J. The multipolar mode and neuronal migration disorders.
    Trends in Neuroscience (2006). 27(7) 407.
  31. McClure MM, Threlkeld SW, Rosen GD, Holly Fitch R. Rapid auditory processing and learning deficits in rats with P1 versus P7 neonatal hypoxic-ischemic injury. Behav Brain Res. 2006;172(1):114-21.
  32. McClure, M., Threlkeld, S. & Fitch, R.H. 2006a. The effects of erythropoietin on auditory processing following neonatal hypoxic-ischemic injury. Brain Research, 1087, 190 – 195.
  33. McClure, M., Threlkeld, S. & Fitch, R.H. 2006c. Auditory processing and learning/memory following erythropoietin administration in neonatally HI injured rats. Brain Research, 1132, 203 – 209.
  34. Mobbs D, Eckert MA, Mills D, Korenberg J, Bellugi U, Galaburda AM, Reiss AL. Frontostriatal Dysfunction During Response Inhibition in Williams Syndrome. Biol Psychiatry. 2006.
  35. Paracchini, S., et al., The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration. Hum Mol Genet, 2006. 15(10): p. 1659-66.
  36. Peirce JL, Li H, Wang J, Manly KF, Hitzemann RJ, Belknap JK, Rosen GD, Goodwin S, Sutter TR, Williams RW, Lu L. How replicable are mRNA expression QTL? Mamm Genome. 2006;17(6):643-56.
  37. Ramos, R.L., J. Bai, and J.J. Loturco, Heterotopia Formation in Rat but Not Mouse Neocortex after RNA Interference Knockdown of DCX. Cereb Cortex, 2006.
  38. Rosen GD, Mesples B, Hendriks M, Galaburda AM. Histometric changes and cell death in the thalamus after neonatal neocortical injury in the rat. Neuroscience. 2006;141(2):875-88.
  39. Threlkeld SW, McClure MM, Rosen GD, Fitch RH. Developmental timeframes for induction of microgyria and rapid auditory processing deficits in the rat. Brain Res. 2006;1109(1):22-31.
  40. Wang Y, Paramasivam M, Thomas A, Bai J, Kaminen-Ahola N, Kere J, Voskuil J, Rosen GD, Galaburda AM, Loturco JJ. DYX1C1 functions in neuronal migration in developing neocortex. Neuroscience. 2006.
  41. Chang BS, Ly J, Appignani B, Bodell A, Apse KA, Ravenscroft RS, Sheen VL, Doherty MJ, Hackney DB, O'Connor M, Galaburda AM, Walsh CA. Reading impairment in the neuronal migration disorder of periventricular nodular heterotopia. Neurology. 2005;64(5):799-803.
  42. Eckert MA, Hu D, Eliez S, Bellugi U, Galaburda A, Korenberg J, Mills D, Reiss AL. Evidence for superior parietal impairment in Williams syndrome. Neurology. 2005;64(1):152-3
  43. .Holinger DP, Bellugi U, Mills DL, Korenberg JR, Reiss AL, Sherman GF, Galaburda AM. Relative sparing of primary auditory cortex in Williams Syndrome. Brain Res. 2005;1037(1-2):35-42.
  44. Li, R.W., et al., Disruption of postsynaptic GABA receptor clusters leads to decreased GABAergic innervation of pyramidal neurons. J Neurochem, 2005. 95(3): p. 756-70.
  45. McClure, M.M. & Fitch, R.H. 2005. Hormones. Entry in “The Encyclopedia of Human Development, “ N.J. Salkind (Ed.), Sage Publications, p.646 - 649.
  46. McClure MM, Peiffer AM, Rosen GD, Fitch RH. Auditory processing deficits in rats with neonatal hypoxic-ischemic injury. Int J Dev Neurosci. 2005;23(4):351-62.
  47. McClure MM, Threlkeld SW, Rosen GD, Holly Fitch R. Auditory processing deficits in unilaterally and bilaterally injured hypoxic-ischemic rats. Neuroreport. 2005;16(12):1309-12.
  48. Meng, H., et al., DCDC2 is associated with reading disability and modulates neuronal development in the brain. Proc Natl Acad Sci U S A, 2005. 102(47): p. 17053-8.
  49. Peiffer AM, McClure MM, Threlkeld SW, Rosen GD, Holly Fitch R. Severity of focal microgyria and associated rapid auditory processing deficits. Neuroreport. 2004;15(12):1923-6.
  50. Peiffer AM, Friedman JT, Rosen GD, Fitch RH. Impaired gap detection in juvenile microgyric rats. Brain Res Dev Brain Res. 2004;152(2):93-8.
  51. Pignatelli, A., et al., Functional Properties of Adult-born Juxtaglomerular Cells in the Mammalian Olfactory Bulb. Chem Senses, 2005. 30 Suppl 1: p. i119-i120.
  52. Sajdel-Sulkowska EM, Nguon K, Sulkowski ZL, Rosen GD, Baxter MG. Purkinje cell loss accompanies motor impairment in rats developing at altered gravity. Neuroreport. 2005;16(18):2037-2040.
  53. Thompson PM, Lee AD, Dutton RA, Geaga JA, Hayashi KM, Eckert MA, Bellugi U, Galaburda AM, Korenberg JR, Mills DL, Toga AW, Reiss AL. Abnormal cortical complexity and thickness profiles mapped in Williams syndrome. J Neurosci. 2005;25(16):4146-58.
  54. Churchill GA, Ö Rosen GD, Ö Zou F, The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet. 2004;36(11):1133-7.
  55. Denenberg, V.D. & Fitch, R.H. 2004. Invited commentary on “Corpus callosum: relative size versus controlling for size” (Smith, R.J.). Current Anthropology, 46 (2), 263 – 264.
  56. Fitch, R.H. & Tallal, P. 2003. Neural mechanisms of language based learning impairments: Insights from human populations and animal models. Behavioral and Cognitive Neuroscience Reviews, 2 (3), 155 - 178.
  57. Gefen S, Tretiak O, Bertrand L, Rosen GD, Nissanov J. Surface alignment of an elastic body using a multiresolution wavelet representation. IEEE Trans Biomed Eng. 2004;51(7):1230-41.
  58. Friedman, J.T., Peiffer, A., Clark, M., Benasich, A. & Fitch, R.H. 2004. Age and experience related improvements in gap detection in the rat. Developmental Brain Research, 152, 83 - 91.
  59. LoTurco, J., Doublecortin and a tale of two serines. Neuron, 2004. 41(2): p. 175-7.
  60. Peiffer AM, Rosen GD, Fitch RH. Sex differences in rapid auditory processing deficits in microgyric rats. Brain Res Dev Brain Res. 2004;148(1):53-7.
  61. Reiss AL, Eckert MA, Rose FE, Karchemskiy A, Kesler S, Chang M, Reynolds MF, Kwon H, Galaburda A. An experiment of nature: brain anatomy parallels cognition and behavior in Williams syndrome. J Neurosci. 2004;24(21):5009-15.
  62. Tallal, P.T. & Fitch, R.H. 2004. Central auditory processing and language learning impairments: Implications for neuroplasticity research. In Plasticity Of The Central Auditory System And Processing Of Complex Acoustic Signals, J. Syka (ed.), Kluwer Plenum Press, in press.
  63. Abiola O, Ö Rosen GD, Ö Zou F, The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet. 2003;4(11):911-6.
  64. Bai, J., et al., RNAi reveals doublecortin is required for radial migration in rat neocortex. Nat Neurosci, 2003. 6(12): p. 1277-83.
  65. Belluzzi, O., et al., Electrophysiological differentiation of new neurons in the olfactory bulb. J Neurosci, 2003.23(32): p. 10411-8.
  66. Galaburda AM, Holinger D, Mills D, Reiss A, Korenberg JR, Bellugi U. [Williams syndrome. A summary of cognitive, electrophysiological, anatomofunctional, microanatomical and genetic findings]. Rev Neurol. 2003;36 Suppl 1:S132-7.
  67. Galaburda AM, Cestnick L. [Developmental dyslexia]. Rev Neurol. 2003;36 Suppl 1:S3-9.
  68. Galaburda AM, Duchaine BC. Developmental disorders of vision. Neurol Clin. 2003;21(3):687-707
  69. Gardella D, Hatton WJ, Rind HB, Rosen GD, von Bartheld CS. Differential tissue shrinkage and compression in the z-axis: implications for optical disector counting in vibratome-, plastic- and cryosections. J Neurosci Methods. 2003;124(1):45-59.
  70. Gardner D, Ö Rosen GD, RÖ Wong ST. Towards effective and rewarding data sharing. Neuroinformatics. 2003;1(3):289-95.
  71. Fitch, RH & Chrobak, JJ. 2003. Animal models of neuropsychological function, In Experimental Methods in Neuropsychology, K. Hugdahl (ed.). Special Issue of Neuropsychology and Cognition (vol. 21), Kluwer Academic Publishers, Boston, MA. p. 89 – 109.
  72. Fitch, R.H. 2003. Learning disabilities. In J. Byrne (ed.) Learning and Memory, 2nd edition (a revised and updated edition of Encyclopedia of Learning and Memory), Macmillan Press, New York, New York. p. 320 - 325.
  73. LoTurco, J.J., et al., Citron kinase is a regulator of mitosis and neurogenic cytokinesis in the neocortical ventricular zone. Cereb Cortex, 2003. 13(6): p. 588-91.
  74. Peiffer AM, Fitch RH, Thomas JJ, Yurkovic AN, Rosen GD. Brain weight differences associated with induced focal microgyria. BMC Neurosci. 2003;4(1):12.
  75. Rosen GD, La Porte NT, Diechtiareff B, Pung CJ, Nissanov J, Gustafson C, Bertrand L, Gefen S, Fan Y, Tretiak OJ, Manly KF, Park MR, Williams AG, Connolly MT, Capra JA, Williams RW. Informatics center for mouse genomics: the dissection of complex traits of the nervous system. Neuroinformatics. 2003;1(4):327-42.
  76. Seecharan DJ, Kulkarni AL, Lu L, Rosen GD, Williams RW. Genetic control of interconnected neuronal populations in the mouse primary visual system. J Neurosci. 2003;23(35):11178-88.
  77. Zygourakis CC, Rosen GD. Quantitative trait loci modulate ventricular size in the mouse brain. J Comp Neurol. 2003;461(3):362-9.
  78. Gabel, L.A. and J.J. LoTurco, Layer I ectopias and increased excitability in murine neocortex. J Neurophysiol, 2002. 87(5): p. 2471-9.
  79. Peiffer AM, Rosen GD, Fitch RH. Rapid auditory processing and MGN morphology in microgyric rats reared in varied acoustic environments. Brain Res Dev Brain Res. 2002;138(2):187-93.
  80. Galaburda AM, Holinger DP, Bellugi U, Sherman GF. Williams syndrome: neuronal size and neuronal-packing density in primary visual cortex. Arch Neurol. 2002;59(9):1461-7.
  81. Peiffer AM, Rosen GD, Fitch RH. Sex differences in rapid auditory processing deficits in ectopic BXSB/MpJ mice. Neuroreport. 2002;13(17):2277-80\
  82. Sarkisian, M.R., et al., Citron-kinase, a protein essential to cytokinesis in neuronal progenitors, is deleted in the flathead mutant rat. J Neurosci, 2002. 22(8): p. RC217.
  83. Schmitt JE, Watts K, Eliez S, Bellugi U, Galaburda AM, Reiss AL. Increased gyrification in Williams syndrome: evidence using 3D MRI methods. Dev Med Child Neurol. 2002;44(5):292-5.
  84. Gabel, L.A. and J.J. LoTurco, Electrophysiological and morphological characterization of neurons within neocortical ectopias. J Neurophysiol, 2001. 85(2): p. 495-505.Peiffer AM, Dunleavy CK, Frenkel M, Gabel LA, LoTurco JJ, Rosen GD,
  85. Galaburda AM, Schmitt JE, Atlas SW, Eliez S, Bellugi U, Reiss AL. Dorsal forebrain anomaly in Williams syndrome. Arch Neurol. 2001;58(11):1865-9.
  86. Fitch RH. Impaired detection of variable duration embedded tones in ectopic NZB/BINJ mice. Neuroreport. 2001;12(13):2875-9.
  87. Peiffer, A.M., et al., Impaired detection of variable duration embedded tones in ectopic NZB/BINJ mice. Neuroreport, 2001. 12(13): p. 2875-9.
  88. Rosen GD, Williams RW. Complex trait analysis of the mouse striatum: independent QTLs modulate volume and neuron number. BMC Neurosci. 2001;2(1):5.
  89. Rosen GD, Windzio H, Galaburda AM. Unilateral induced neocortical malformation and the formation of ipsilateral and contralateral barrel fields. Neuroscience. 2001;103(4):931-9.
  90. Sarkisian, M.R., et al., Altered interneuron development in the cerebral cortex of the flathead mutant. Cereb Cortex, 2001. 11(8): p. 734-43.
  91. Bimonte, HA., Fitch, RH. & Denenberg, VH. 2000a. Adult ovary transfer counteracts the callosal enlargement resulting from prepubertal ovariectomy. Brain Research, 872, 254 - 257.
  92. Bimonte, HA., Fitch, RH. & Denenberg, VH. 2000b. Neonatal estrogen blockade prevents normal callosal responsiveness to estrogen in adulthood. Developmental Brain Research, 122, 149 - 155.
  93. Chang, S.L., J.J. LoTurco, and L.K. Nisenbaum, In vitro biocytin injection into perinatal mouse brain: a method for tract tracing in developing tissue. J Neurosci Methods, 2000. 97(1): p. 1-6.
  94. Clark MG, Rosen GD, Tallal P, Fitch RH. Impaired two-tone processing at rapid rates in male rats with induced microgyria. Brain Res. 2000;871(1):94-7.
  95. Clark MG, Rosen GD, Tallal P, Fitch RH. Impaired processing of complex auditory stimuli in rats with induced cerebrocortical microgyria: An animal model of developmental language disabilities. J Cogn Neurosci. 2000;12(5):828-39.
  96. Clark, MG., Sherman, GF., Bimonte, HA. & Fitch, RH. 2000a. Perceptual auditory gap detection deficits in ectopic male BXSB mice. NeuroReport, 11, 693-696.
  97. Clark, M., Rosen, G., Tallal, P. & Fitch, RH. 2000b. Impaired processing of complex auditory stimuli in rats with induced cerebrocortical microgyria. J Cog Neurosci, 12 (5), 828 – 839.
  98. Galaburda AM, Bellugi U. V. Multi-level analysis of cortical neuroanatomy in Williams syndrome. J Cogn Neurosci. 2000;12 Suppl 1:74-88.
  99. Gogal RM, Ahmed SA, Holladay SD, Walsh JE, Galaburda AM, Rosen GD. Induced minor malformations in the neocortex of normal mice do not alter immunological functions. Immunol Invest. 2000;29(3):299-318.
  100. Fitch, RH., Read, HL. & Benasich, AA. 2000. Neurophysiology of speech perception in normal and impaired systems. In Physiology of the Ear, A.F. Jahn & J. Santos-Sachi (Eds.). Singular Thompson Learning, p. 651 - 671.
  101. Frenkel, M., et al., Neocortical ectopias are associated with attenuated neurophysiological responses to rapidly changing auditory stimuli. Neuroreport, 2000. 11(3): p. 575-9.
  102. Frenkel M, Sherman GF, Bashan KA, Galaburda AM, LoTurco JJ. Neocortical ectopias are associated with attenuated neurophysiological responses to rapidly changing auditory stimuli. Neuroreport. 2000;11(3):575-9.
  103. Jenner AR, Galaburda AM, Sherman GF. Connectivity of ectopic neurons in the molecular layer of the somatosensory cortex in autoimmune mice. Cereb Cortex. 2000;10(10):1005-13.
  104. Li, W. and J.J. LoTurco, Noggin is a negative regulator of neuronal differentiation in developing neocortex. Dev Neurosci, 2000. 22(1-2): p. 68-73.
  105. LoTurco, J.J., Neural circuits in the 21st century: synaptic networks of neurons and glia. Proc Natl Acad Sci U S A, 2000. 97(15): p. 8196-7.
  106. Pennington BF, Filipek PA, Lefly D, Chhabildas N, Kennedy DN, Simon JH, Filley CM, Galaburda A, DeFries JC. A twin MRI study of size variations in human brain. J Cogn Neurosci. 2000;12(1):223-32.

  107. Roberts, M.R., et al., The flathead mutation causes CNS-specific developmental abnormalities and apoptosis. J Neurosci, 2000. 20(6): p. 2295-306.
  108. Rosen GD, Burstein D, Galaburda AM. Changes in efferent and afferent connectivity in rats with induced cerebrocortical microgyria. J Comp Neurol. 2000;418(4):423-40.

  109. Rosen GD, Galaburda AM. Single cause, polymorphic neuronal migration disorders: an animal model. Dev Med Child Neurol. 2000;42(10):652-62.


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